Type 2 diabetes mellitus (T2DM) patients are highly susceptible to developing dementia, especially for housing those with mild cognitive impairment (MCI), but its underlying cause is still unclear.In this study, we performed a battery of neuropsychological tests and high-resolution sagittal T1-weighted structural imaging to explore how T2DM affects
Owing to their pleiotropic metabolic benefits, glucagon-like peptide-1 receptor (GLP-1R) agonists have been successfully utilized for treating metabolic diseases, such as type 2 diabetes and obesity.As part of our efforts in developing long-acting peptide therapeutics, we have previously reported a peptide engineering strategy that combines peptide
Barnacles of the genus Chthamalus are commonly encountered rocky intertidal shores.The phylogeography of the different species in the Western Indian Ocean is unclear.Using morphological characteristics as well as the molecular markers mitochondrial cytochrome oxygenase subunit I (COI) and the nuclear sodium-potassium ATPase (NaKA), we identified fo
It is without doubt the case that memory of the past has been and is being used in certain places to 3mm justify radical intolerance and unspeakable violence.But for every instance where that is the case, a dozen alternative cases exist where memory creates cohesion, positive change, and a less violent society.This article focuses on the instances
Atopic dermatitis (AD) is a complex inflammatory skin condition that is not fully understood.Epidermal barrier defects and Th2 immune response dysregulations are thought to play crucial roles in the pathogenesis of the disease.A vicious circle takes place between these alterations, and it can further be complicated by additional genetic and environ